Article

African-specific genetic loci determine iron status and risk of severe malaria and bacteremia in African children

2025-03-05

Abstract excerpt

Iron is an essential trace element for both humans and pathogens, but its genetic determinants are understudied in Africa where iron deficiency and infectious diseases are highly prevalent. We conducted genome-wide association studies for six iron-related biomarkers in 3928 children from five sites across Africa with replication in 2868 African American adults. We identified previously unreported loci for transfer...

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Literature Corpus work: c1737c16-dc5d-598a-8f69-585aecec5512
DOI: 10.1101/2025.03.02.25323069

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