Article

Ropinirole hydrochloride for amyotrophic lateral sclerosis: A single-center, randomized feasibility, double-blind, placebo-controlled trial

2021-12-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> We previously used an induced pluripotent stem cell-based drug repurposing approach to demonstrate that ropinirole hydrochloride (ropinirole) attenuated amyotrophic lateral sclerosis (ALS)-specific pathological phenotypes. Here, we assessed the safety and feasibility of ropinirole in ALS patients to verify its efficacy. <h4>Methods</h4> We conducted a randomized feasibility tr...

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Literature Corpus work: 2c6c6948-2ec4-5842-bd4e-569e64d2058b
DOI: 10.1101/2021.12.05.21267266

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