Article

Preclinical testing of potential therapeutics for Amyotrophic Lateral Sclerosis

2012-01-01

Abstract excerpt

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurological disorder caused by the selective degeneration of upper and lower motor neurons, for which there are currently no effective treatments. 10% of ALS cases are familial, of which 15-20% are caused by mutations in the copper/zinc superoxide dismutase gene (SOD1). The primary triggers for motor neuron degeneration in ALS are unknown, but research in patients an...

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Literature Corpus work: 08f10b4d-1941-52ee-b7f0-b05f10e42cdd
DOI: 10.25560/9606

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