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Ropinirole hydrochloride remedy for amyotrophic lateral sclerosis - Protocol for a randomized, double-blind, placebo-controlled, single-center, and open-label continuation phase I/IIa clinical trial (ROPALS trial)

2019-01-10

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<title>Abstract</title> <p><bold>Background:</bold> Amyotrophic lateral sclerosis (ALS) is one of intractable neurological diseases, which is an incurable disease. ALS is a progressive disease characterized by muscle atrophy and weakness caused by selective vulnerability of upper and lower motor neurons. In the disease research ever conducted, it has been common to use mouse models carrying mutations in responsib...

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Literature Corpus work: 6d6862f5-d35f-52ee-b3bb-0a9a5388366b
DOI: 10.21203/rs.2.207/v1

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