Article

Spinal Cord Motor Neuron Phenotypes and Polygenic Risk Scores in Sporadic Amyotrophic Lateral Sclerosis: Deciphering the Disease Pathology and Therapeutic Potential of Ropinirole Hydrochloride

2024-03-07

Abstract excerpt

<h4>ABSTRACT</h4> This study investigated the genetic factors associated with the onset of amyotrophic lateral sclerosis (ALS) and the mechanism of action of Ropinirole hydrochloride (ROPI) in ALS treatment. Firstly, ALS is a neurodegenerative disease characterized by the degeneration of both upper and lower motor neurons (MNs), and identifying the genetic factors of sporadic ALS (SALS) has been challenging. Howev...

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Literature Corpus work: 298b656f-6086-5352-b652-9de6a0ee1a0c
DOI: 10.1101/2024.03.04.24303652

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Spinal Cord Motor Neuron Phenotypes and Polygenic Risk Scores in Sporadic Amyotrophic Lateral Sclerosis: Deciphering the Disease Pathology and Therapeutic Potential of Ropinirole HydrochlorideDOI 10.1101/2024.03.04.24303652Read

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