Article

Behavioral and psychological symptoms of dementia: insights from a multivariate and network-based brain proteome-wide study

2026-04-24

Abstract excerpt

Behavioral and psychological symptoms of dementia (BPSD) are common, profoundly troubling to patients and caregivers, and difficult to treat, yet their molecular underpinnings remain poorly understood. Here, we generated a large brain proteomic dataset with nine BPSD domains assessed in life from 376 donors from three cohorts. Protein associations with BPSD were examined using complementary approaches — domain-spe...

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Literature Corpus work: 2c6bccb0-452c-52a2-86d9-b0878343f9c6
DOI: 10.64898/2026.04.23.26351110

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