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A single-cell atlas of Plasmodium falciparum transmission through the mosquito

27 May 2021

Abstract excerpt

Malaria parasites have a complex life cycle featuring diverse developmental strategies, each uniquely adapted to navigate specific host environments. Here we use single-cell transcriptomics to illuminate gene usage across the transmission cycle of the most virulent agent of human malaria - Plasmodium falciparum. We reveal developmental trajectories associated with the colonization of the mosquito midgut and...

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PMID: 34045457
DOI: 10.1038/s41467-021-23434-z

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