Article

A <i>MEF2C</i> transcription factor network regulates proliferation of glomerular endothelial cells in diabetic kidney disease

2024-09-30

Abstract excerpt

The maintenance of a healthy epithelial-endothelial juxtaposition requires cross-talk within glomerular cellular niches. We sought to understand the spatially-anchored regulation and transition of endothelial and mesangial cells from health to injury in DKD. From 74 human kidney samples, an integrated multi-omics approach was leveraged to identify cellular niches, cell-cell communication, cell injury trajectories,...

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Literature Corpus work: 2c58cf75-1397-52c3-8d1c-7674a6fe23cc
DOI: 10.1101/2024.09.27.615250

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