Article

Doublecortin-expressing cells are selectively altered in the piriform cortex but not in neurogenic areas of symptomatic Mecp2-heterozygous mice

2025-08-18

Abstract excerpt

<title>Abstract</title> <p> Rett Syndrome (RTT) is a neurodevelopmental disorder which mainly affects girls, leading to profound impairments in motor function, loss of speech, intellectual disability, and epilepsy, among other symptoms. Most cases are caused by mutations in the X-linked <italic>MECP2</italic> gene, which encodes the protein methyl-CpG-binding protein 2 (MeCP2), an epigenetic reader with a cruc...

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Literature Corpus work: 2c50e819-559a-58d7-9dd6-9bb3da4c0d81
DOI: 10.21203/rs.3.rs-7269766/v1

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