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Withaferin A reduces pulmonary eosinophilia and IL-25 production in a mouse model of allergic airways disease

2024-08-26

Abstract excerpt

Several studies report that ashwagandha, a traditional Ayurvedic supplement, has anti-inflammatory properties. Type 2 (T2) asthma is characterized by eosinophilic airway inflammation. We hypothesized that allergen-induced eosinophilic airway inflammation in mice would be reduced following administration of Withaferin A (WFA), the primary active phytochemical in Ashwagandha. C57BL/6J mice were given 10 total intra-...

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Identifiers and source

Literature Corpus work
2c2d9cfb-2530-5d6a-baac-b978489b073e
DOI
10.1101/2024.08.26.609636
Open publication

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Withaferin A reduces pulmonary eosinophilia and IL-25 production in a mouse model of allergic airways diseaseDOI 10.1101/2024.08.26.609636
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