Iristectorigenin A exerts novel protective properties against airway inflammation and mucus hypersecretion in OVA-induced asthmatic mice: Iristectorigenin A ameliorates asthma phenotype.

doi:10.1016/j.phymed.2022.154252

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Iristectorigenin A exerts novel protective properties against airway inflammation and mucus hypersecretion in OVA-induced asthmatic mice: Iristectorigenin A ameliorates asthma phenotype.

Phytomedicine : international journal of phytotherapy and phytopharmacology - 1 Sept 2022

Wuniqiemu Tulake, Teng Fangzhou, Qin Jingjing, Lv Yubao, Nabijan Mohammadtursun, Luo Qingli, Zhou Yaolong, Cui Jie, Yi La, Tang Weifeng, Zhu Xueyi, Amangu, Wang Shiyuan, Abduwaki Muhammadjan, Nurahmat Mammat, Wei Ying, Dong Jing Cheng

Abstract excerpt

BACKGROUND: Despite the substantial amount of efforts made to reduce morbidity and improve respiratory management, asthma control remained a major challenge for severe patients. Plant isoflavones, one of the most estrogenic compounds, are considered a potential alternative therapy for asthma. Iristectorigenin A, a naturally occurring isoflavone, is extracted from a variety of medical plants and its biological...

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PMID: 35752075
DOI: 10.1016/j.phymed.2022.154252

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