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New insights into the function of Interleukin-25 in disease pathogenesis

1 Apr 2023

Abstract excerpt

Interleukin-25 (IL-25), also known as IL-17E, is a cytokine belonging to the IL-17 family. IL-25 is abundantly expressed by Th2 cells and various kinds of epithelial cells. IL-25 is an alarm signal generated upon cell injury or tissue damage to activate immune cells through the interaction with IL-17RA and IL-17RB receptors. The binding of IL-25 to IL-17RA/IL-17RB complex not only initiates and maintains type 2...

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PMID: 37005677
DOI: 10.1186/s40364-023-00474-9

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