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Article

Time‐dependent distinct roles of Toll‐like receptor 4 in a house dust mite‐induced asthma mouse model

16 Jan 2018

Abstract excerpt

House dust mites (HDMs) are a common source of allergens that trigger both allergen-specific and innate immune responses in humans. Here, we examined the effect of allergen concentration and the involvement of Toll-like receptor 4 (TLR4) in the process of sensitization to house dust mite allergens in an HDM extract-induced asthma mouse model. Intranasal administration of HDM extract induced an immunoglobulin E...

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Share to Allergic Rhinitis and Sensitization
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PMID: 29337391
DOI: 10.1111/sji.12641

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