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Article

A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity.

The Journal of experimental medicine - 24 Nov 2008

Terashima Asuka, Watarai Hiroshi, Inoue Sayo, Sekine Etsuko, Nakagawa Ryusuke, Hase Koji, Iwamura Chiaki, Nakajima Hiroshi, Nakayama Toshinori, Taniguchi Masaru

Abstract excerpt

Airway hypersensitive reaction (AHR) is an animal model for asthma, which is caused or enhanced by environmental factors such as allergen exposure. However, the precise mechanisms that drive AHR remain unclear. We identified a novel subset of natural killer T (NKT) cells that expresses the interleukin 17 receptor B (IL-17RB) for IL-25 (also known as IL-17E) and is essential for the induction of AHR. IL-17RB is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19015310
DOI: 10.1084/jem.20080698
PMCID: PMC2585837

Genes

AHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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