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Article

Overexpression of MicroRNA-25 by Withaferin A Induces Cyclooxygenase-2 Expression in Rabbit Articular Chondrocytes

1 Jan 2014

Abstract excerpt

Increasing evidence supports the role of microRNAs (miRNA) in the regulation of inflammation in various human disorders. Several recent studies have demonstrated that microRNA-25 (miR-25) has multiple functions, and it affects the expression of inflammatory mediators. Withaferin A (WFA), a natural compound derived from the medicinal plant Withania somnifera, has shown the potential to be an effective drug for...

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PMID: 24748433
DOI: 10.1254/jphs.13232fp

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