Article

Doxycycline reversal of amphetamine-induced mania-like behavior is related to adjusting brain monoamine abnormalities and antioxidant effects in primary hippocampal neurons.

2023-08-10

Abstract excerpt

<h4>Purpose: </h4> Mania is associated with disturbed dopaminergic transmission in frontotemporal regions. D-amphetamine (AMPH) causes increased extracellular DA levels, considered an acknowledged mania model in rodents. Doxycycline (DOXY) is a second-generation tetracycline with promising neuroprotective properties. Here, we tested the hypothesis that DOXY alone or combined with Lithium (Li) could reverse AMPH-in...

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Literature Corpus work: 2c0af1b3-ced0-5a31-b700-1e10f0b2abf6
DOI: 10.21203/rs.3.rs-3220970/v1

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Doxycycline reversal of amphetamine-induced mania-like behavior is related to adjusting brain monoamine abnormalities and antioxidant effects in primary hippocampal neurons.DOI 10.21203/rs.3.rs-3220970/v1Read

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