Article

Imaging progenitor cell differentiation during central nervous system remyelination using an MRI gene reporter

2025-09-15

Abstract excerpt

<h4>Summary</h4> Demyelination, the loss of the myelin sheath from around otherwise intact axons, occurs in several diseases, most notably multiple sclerosis (MS). Demyelinated axons that are not remyelinated are vulnerable to irreversible degeneration and therefore therapies that enhance remyelination have been sought. However, there remains a paucity of suitable outcome measures to assess their efficacy. Magnet...

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Literature Corpus work: 2bf574ea-bb2a-558d-896b-8b8325d16ec4
DOI: 10.1101/2025.09.10.674209

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