Article

Imaging myelin basic protein expression in a model of remyelination by magnetic resonance imaging using an organic anion transporter protein gene reporter system

2018-01-01

Abstract excerpt

Demyelination occurs in several CNS diseases. If demyelinated axons are not remyelinated they become vulnerable to irreversible degeneration. There is, therefore, a clinical need for therapies that enhance remyelination. This can be achieved by 1) pharmacologically targeting endogenous oligodendrocyte progenitor cells (OPCs) responsible for remyelination or 2) transplantation of myelinogenic cells (including OPCs)...

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Literature Corpus work: fcbe60b8-924c-52b8-af2a-a625a42a9589
DOI: 10.17863/cam.41934

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