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Spatial microenvironments tune immune response dynamics in the <i>Drosophila</i> larval fat body

2024-09-16

Abstract excerpt

Immune responses in tissues display complex spatial patterns of gene expression that are linked to disease outcomes. However, the mechanisms that generate these patterns—including the relative roles of noisy gene expression dynamics, microbial transport, and tissue anatomy— are poorly understood. As a tractable model of spatial immune responses, we investigated heterogeneous expression of antimicrobial peptides in...

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Literature Corpus work
2bb200ba-7442-5dce-85e9-5ffe2683c2a6
DOI
10.1101/2024.09.12.612587
Open publication

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Spatial microenvironments tune immune response dynamics in the <i>Drosophila</i> larval fat bodyDOI 10.1101/2024.09.12.612587
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