Article

A mouse model for spinal muscular atrophy provides insights into non-alcoholic fatty liver disease pathogenesis

2020-04-30

Abstract excerpt

<h4>Background & aims</h4> Spinal muscular atrophy (SMA) is an inherited neuromuscular disorder leading to paralysis and death in children. SMA patients are more susceptible to dyslipidemia as well as liver steatosis, features reproduced in SMA mouse models. As current pre-clinical models of NAFLD are invariably imperfect and generally take a long time to develop, the rapid development of liver steatosis in SMA m...

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Literature Corpus work: 2b80d49c-1c8f-5162-9dad-c1b6ded8b731
DOI: 10.1101/2020.04.29.051938

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