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Mitochondrial Dysfunction Induces Hepatic Lipid Accumulation and Inflammatory Responses in mtDNA Mutator Mice

2025-04-28

Abstract excerpt

<h4>Background</h4> Non-Alcoholic Fatty Liver Disease (NAFLD), now referred to as Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), is a widespread and complex health issue characterized by the accumulation of lipids in liver cells, not linked to alcohol consumption or other known liver problems. Despite its strong association with insulin resistance and obesity, a notable proportion of lean indiv...

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Literature Corpus work
9c2ed02f-c078-50cf-9676-5becb4ce9ce2
DOI
10.1101/2025.04.25.650453
Open publication

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Mitochondrial Dysfunction Induces Hepatic Lipid Accumulation and Inflammatory Responses in mtDNA Mutator MiceDOI 10.1101/2025.04.25.650453
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