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Article

Ketogenic diet attenuates hepatopathy in mouse model of respiratory chain complex III deficiency caused by a Bcs1l mutation.

Scientific reports - 19 Apr 2017

Purhonen Janne, Rajendran Jayasimman, Mörgelin Matthias, Uusi-Rauva Kristiina, Katayama Shintaro, Krjutskov Kaarel, Einarsdottir Elisabet, Velagapudi Vidya, Kere Juha, Jauhiainen Matti, Fellman Vineta, Kallijärvi Jukka

Abstract excerpt

Mitochondrial disorders are among the most prevalent inborn errors of metabolism but largely lack treatments and have poor outcomes. High-fat, low-carbohydrate ketogenic diets (KDs) have shown beneficial effects in mouse models of mitochondrial myopathies, with induction of mitochondrial biogenesis as the suggested main mechanism. We fed KD to mice with respiratory chain complex III (CIII) deficiency and...

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Share to ATPases Associated with Diverse Cellular Activities
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28424480
DOI: 10.1038/s41598-017-01109-4
PMCID: PMC5430426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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