Article

Schlafen 11 Restricts Flavivirus Replication

2018-10-03

Abstract excerpt

<h4>ABSTRACT</h4> Schlafen 11 (Slfn11) is a ubiquitously expressed interferon stimulating gene (ISG) that controls synthesis of proteins by regulating tRNA abundance. Likely through this mechanism, Slfn11 has previously been shown to impair human immunodeficiency virus 1 (HIV-1) infection and the expression of codon-biased open reading frames. Because replication of positive-sense single-stranded RNA [(+)ssRNA vi...

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Literature Corpus work: 2b759baa-80c4-5adc-a97a-c33b56033f72
DOI: 10.1101/434563

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