Article

Translational profiling of microglia reveals artifacts of cell sorting

2017-05-09

Abstract excerpt

Microglia are the resident innate immune population of the central nervous system that constantly survey and influence their local environment. Transcriptomic profiling has led to significant advances in our understanding of microglia in several disease states, but tissue dissociation and purification of microglia is known to lead to cellular activation. Here we use RiboTag translational RNAseq profiling to demons...

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Identifiers and source

Literature Corpus work: 2b5533b7-81bd-56ad-860e-205c9f18fd14
DOI: 10.1101/135566

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