Article
Shared molecular networks in orofacial and neural tube development.
Birth defects research - 30 Jan 2017
Kousa Youssef A, Mansour Tamer A, Seada Haitham, Matoo Samaneh, Schutte Brian C
Abstract excerpt
BACKGROUND: Single genetic variants can affect multiple tissues during development. Thus it is possible that disruption of shared gene regulatory networks might underlie syndromic presentations. In this study, we explore this idea through examination of two critical developmental programs that control orofacial and neural tube development and identify shared regulatory factors and networks. Identification of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.