Insights into Keratinocyte and Immunologic Landscape in Cutaneous Graft-Versus-Host Disease through Single-Cell Transcriptomics

Abstract excerpt

Cutaneous manifestations are the most common presenting sign of chronic graft-versus-host disease (GVHD), and the extent of cutaneous involvement is also highly correlated with prognosis. Very little is understood about the underlying pathogenesis underpinning injury at this location, especially the contribution of keratinocytes and other structural skin cells. We performed single-cell RNA sequencing to compare...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Corneal Surgery and Treatments
• Share to Hematopoietic Stem Cell Transplantation
• Share to Skin Protection and Aging