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Article

The heterogeneity of lung macrophages in the susceptibility to disease.

European respiratory review : an official journal of the European Respiratory Society - 1 Sept 2015

Morales-Nebreda Luisa, Misharin Alexander V, Perlman Harris, Budinger G R Scott

Abstract excerpt

Alveolar macrophages are specialised resident phagocytes in the alveolus, constituting the first line of immune cellular defence in the lung. As the lung microenvironment is challenged and remodelled by inhaled pathogens and air particles, so is the alveolar macrophage pool altered by signals that maintain and/or replace its composition. The signals that induce the recruitment of circulating monocytes to the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26324812
DOI: 10.1183/16000617.0031-2015
PMCID: PMC9487691

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