Article
No evidence for transvection <i>in vivo</i> by a superenhancer:promoter pair integrated into identical open chromatin at the <i>Rosa26</i> locus
2018-08-16
Abstract excerpt
Long-range associations between enhancers and their target gene promoters have been shown to play critical roles in executing genome function. Recent variations of chromosome capture technology have revealed a conprehensive view of intra- and inter-chromosomal contacts between specific genomic sites. The locus control region of the β-globin genes (β-LCR) is a super-enhancer that is capable of activating all of the...
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Identifiers and source
- Literature Corpus work
- 2b146f3a-f2a3-5386-bd71-dfb63f7580c7
- DOI
- 10.1101/393363
