Article

A biophysical study of the p53-DNA interactions at the single-molecule level

2015-01-01

Abstract excerpt

The p53 protein has been widely studied since its discovery as a tumour suppressor protein in 1989 with applications in cancer diagnostics and anti-cancer therapy. p53 has been found to be mutated in 50% of human cancers. Therefore, understanding the properties, mechanisms and mutations of the protein is undoubtedly of great importance in the pursuit of understanding and treating cancer. In this thesis, single mol...

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Literature Corpus work: 2b083e75-2bea-507c-bdac-40538e2f2870
DOI: 10.25560/32114

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