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Kelvin probe force microscopy of DNA-capped nanoparticles for single-nucleotide polymorphism detection.

Nanoscale - 14 Jul 2016

Lee Hyungbeen, Lee Sang Won, Lee Gyudo, Lee Wonseok, Lee Jeong Hoon, Hwang Kyo Seon, Yang Jaemoon, Lee Sang Woo, Yoon Dae Sung

Abstract excerpt

Kelvin probe force microscopy (KPFM) is a robust toolkit for profiling the surface potential (SP) of biomolecular interactions between DNAs and/or proteins at the single molecule level. However, it has often suffered from background noise and low throughput due to instrumental or environmental constraints, which is regarded as limiting KPFM applications for detection of minute changes in the molecular structures...

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PMID: 27127876
DOI: 10.1039/c5nr08969g

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BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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