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Article

Estimating interaction between genetic and environmental risk factors: efficiency of sampling designs within a cohort.

Epidemiology (Cambridge, Mass.) - 1 Jan 2008

Bureau Alexandre, Diallo Mamadou S, Ordovas Jose M, Cupples L Adrienne

Abstract excerpt

Large prospective cohorts originally assembled to study environmental risk factors are increasingly exploited to study gene-environment interactions. Given the cost of genetic studies in large samples, being able to select a subsample for genotyping that contains most of the information from the cohort would lead to substantial savings. We consider nested case-control and case-cohort sampling designs with and...

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Identifiers

PMID: 18091418
DOI: 10.1097/EDE.0b013e31815c4d0e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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