Article

Single-cell multiome uncovers differences in glycogen metabolism underlying species-specific speed of development

2024-09-03

Abstract excerpt

Embryos from different mammalian species develop at characteristic timescales. These timescales are recapitulated during the differentiation of pluripotent stem cells in vitro . Specific genes and molecular pathways that modulate cell differentiation speed between mammalian species remain to be determined. Here we use single-cell multi-omic analysis of neural differentiation of mouse, cynomolgus and human pluripo...

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Literature Corpus work: 2aee0ec3-4a6c-59d1-8a0a-d89d1f4fccc7
DOI: 10.1101/2024.09.03.610938

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