Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Who’s Driving? Human Cytomegalovirus, Interferon, and NFκB Signaling

21 Aug 2018

Abstract excerpt

As essential components of the host's innate immune response, NFκB and interferon signaling are critical determinants of the outcome of infection. Over the past 25 years, numerous Human Cytomegalovirus (HCMV) genes have been identified that antagonize or modulate the signaling of these pathways. Here we review the biology of the HCMV factors that alter NFκB and interferon signaling, including what is currently...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to Toxoplasma gondii Research Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30134546
DOI: 10.3390/v10090447

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Who’s Driving? Human Cytomegalovirus, Interferon, and NFκB SignalingPMID 30134546Read ↗

Prolonged activation of NF-κB by human cytomegalovirus promotes efficient viral replication and late gene expressionSemantic proximity Read ↗

The Interplay between Human Cytomegalovirus and Pathogen Recognition Receptor SignalingSemantic proximity Read ↗

Chromatin control of human cytomegalovirus infectionSemantic proximity Read ↗

Dynamic roles for NF‐κB in HTLV‐I and HIV‐1 retroviral pathogenesisSemantic proximity Read ↗

Human cytomegalovirus exploits STING signaling and counteracts IFN/ISG induction to facilitate infection of dendritic cellsSemantic proximity Read ↗

Human Cytomegalovirus Latency and Reactivation – A Delicate Balance between the Virus and Its Host’s Immune SystemSemantic proximity Read ↗

Interplay Between CMVs and Interferon Signaling: Implications for Pathogenesis and Therapeutic InterventionSemantic proximity Read ↗

Regulation of the transcription and replication cycle of human cytomegalovirus is insensitive to genetic elimination of the cognate NF-kappaB binding sites in the enhancer.Semantic proximity Read ↗

Molecular Determinants and the Regulation of Human Cytomegalovirus Latency and ReactivationSemantic proximity Read ↗

Human Cytomegalovirus MicroRNAs miR-US5-1 and miR-UL112-3p Block Proinflammatory Cytokine Production in Response to NF-κB-Activating Factors through Direct Downregulation of IKKα and IKKβSemantic proximity Read ↗

HCMV exploits STING signaling and counteracts IFN and ISG induction to facilitate dendritic cell infectionSemantic proximity Read ↗

The Role of Nuclear Factor κB in the Interferon ResponseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.