Article

Hyponatremia Promotes Cancer Growth in a Murine Xenograft Model of Neuroblastoma

2023-10-16

Abstract excerpt

In cancer patients, hyponatremia is detected in about 40% of cases at hospital admission and has been associated to a worse outcome. We have previously observed that cancer cells from differ-ent tissues show a significantly increased proliferation rate and invasion potential, when cul-tured in low extracellular [Na+]. We have recently developed an animal model of hyponatremia using Foxn1nu/nu mice. The aim of the...

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Literature Corpus work: 2a8ff119-ccf6-5840-bdd6-76b46cae99eb
DOI: 10.20944/preprints202310.0905.v1

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