Article
Proteo-transcriptomic analysis reveals brain-region-specific gene and biomarker expression in post-mortem neural tissue of Alzheimer’s patients
2022-11-29
Abstract excerpt
Alzheimer’s disease is a neurodegenerative disorder, marked by dementia, impaired judgment, and a decline in cognitive abilities, that affects over 50 million people worldwide. The etiology of the disease is influenced by a myriad of genetic and environmental factors including APOE4 allele status and sex and can be characterized by a variety of neuropathological markers, such as amyloid-beta (Aβ) plaques and neuro...
Topics
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- Alzheimer's disease research and treatments
- Bioinformatics and Genomic Networks
- Cholinesterase and Neurodegenerative Diseases
- Dementia and Cognitive Impairment Research
- Gene expression and cancer classification
- Neuroinflammation and Neurodegeneration Mechanisms
- Nuclear Receptors and Signaling
- RNA regulation and disease
Identifiers and source
- Literature Corpus work
- 2a87ddb8-89bf-5d31-8d0e-f986dcc49610
- DOI
- 10.1101/2022.11.26.22282736
