Article

Single-Molecule FRET Illuminates Structural Subpopulations and Dissects Crucial Molecular Events During Phase Separation of a Prion-Like Low-Complexity Domain

2023-05-24

Abstract excerpt

Biomolecular condensates formed via phase separation of proteins and nucleic acids are thought to be associated with a wide range of cellular functions and dysfunctions. We dissect critical molecular events associated with phase separation of an intrinsically disordered prion-like low-complexity domain of Fused in Sarcoma by performing single-molecule studies that permit us to access the wealth of molecular inform...

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Literature Corpus work: 2a3550b8-5c79-525a-a683-7f1403f53172
DOI: 10.1101/2023.05.23.541917

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