Article

MicroRNA-27a is a key modulator of cholesterol biosynthesis

2018-08-02

Abstract excerpt

<h4>ABSTRACT</h4> Hypercholesterolemia is a strong predictor of cardiovascular diseases. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase gene ( Hmgcr ) coding for the rate-limiting enzyme in the cholesterol biosynthesis pathway is a crucial regulator of plasma cholesterol levels. However, the post-transcriptional regulation of Hmgcr remains poorly understood. The main objective of this study was to explore the r...

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Literature Corpus work: 2a321828-dce5-5a5b-95df-4d3f0108742e
DOI: 10.1101/383448

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