Article

Vitamin K-dependent carboxylation in osteoblasts regulates bone resorption through GAS6

2025-09-25

Abstract excerpt

<title>Abstract</title> <p> Studies in humans suggest that vitamin K is involved in the regulation of bone remodeling, but the precise mechanism at play remains unknown. In cells, vitamin K functions as a co-factor for the g-glutamyl carboxylase (GGCX), an enzyme responsible for the conversion of glutamic acid residues (Glu) into g-carboxyglutamic acid (Gla) residues in secreted proteins. We aim here at determin...

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Literature Corpus work: 2a282345-c407-5dfc-9e3c-d1bb15887b9b
DOI: 10.21203/rs.3.rs-7472868/v1

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