Back to search

Article

Non-canonical histone H3.3 and its chaperones HIRA and DAXX participate in the regulation of KSHV latency

2026-04-06

Abstract excerpt

Kaposi’s sarcoma-associated herpesvirus (KSHV), also named HHV-8, is the etiological agent of Kaposi sarcoma (KS), Primary effusion lymphoma (PEL), and Multicentric Castleman’s disease. After de novo infection, KSHV genomes rapidly circularize and acquire a chromatin state that favors latency. During latency, the KSHV episome is decorated with distinct epigenetic marks that segregate the viral genome into transcri...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a2166475-a07d-5ba2-ad2d-4005fc0b9ed4
DOI
10.64898/2026.04.02.716100
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Non-canonical histone H3.3 and its chaperones HIRA and DAXX participate in the regulation of KSHV latencyDOI 10.64898/2026.04.02.716100
Epigenetic Regulation of Kaposi’s Sarcoma-Associated Herpesvirus LatencySemantic proximity
Epigenetic Landscape of Kaposi's Sarcoma-Associated Herpesvirus Genome in Classic Kaposi's Sarcoma TissuesSemantic proximity
KSHV LANA—The Master Regulator of KSHV LatencySemantic proximity
Chromatinization of the KSHV Genome During the KSHV Life CycleSemantic proximity
Kaposi’s Sarcoma-Associated Herpesvirus LANA Hitches a Ride on the ChromosomeSemantic proximity
KSHV Genome Replication and MaintenanceSemantic proximity
The Chromatin Landscape of Kaposi’s Sarcoma-Associated HerpesvirusSemantic proximity
Site-Specific Association with Host and Viral Chromatin by Kaposi's Sarcoma-Associated Herpesvirus LANA and Its Reversal during Lytic ReactivationSemantic proximity
LANA Binds to Multiple Active Viral and Cellular Promoters and Associates with the H3K4Methyltransferase hSET1 ComplexSemantic proximity
Kaposi’s Sarcoma Herpesvirus Genome PersistenceSemantic proximity
H2AX Phosphorylation Is Important for LANA-Mediated Kaposi's Sarcoma-Associated Herpesvirus Episome PersistenceSemantic proximity
Enhancer-promoter activation by the Kaposi sarcoma-associated herpesvirus episome maintenance protein LANASemantic proximity
Select a neighboring publication to make it the new centre.