Article

The pivotal role of the AXL/Gas6 signaling node in the mesenchymal subtype of ovarian cancer, and its modulation by the tumor suppressor OPCML

2017-01-01

Abstract excerpt

Epithelial Ovarian Cancer (EOC) is a complex and lethal gynecological malignancy as demonstrated by the heterogeneity in gene expression molecular subtypes (GEMS). To address the GEMS-specific lethality in ovarian cancer, we highlight the relevance of how a receptor tyrosine kinase (RTK) differs in the signaling pattern, functional consequences, and therapeutic implications in the context of GEMS. An enrichment an...

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Literature Corpus work: 299fa30e-a796-58d9-b2dd-ac95d3c8c71f
DOI: 10.25560/69788

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