Article

Multi-omics analysis reveals key immunogenic signatures induced by oncolytic Zika virus infection of paediatric brain tumour cells

2025-03-25

Abstract excerpt

<title>Abstract</title> <p>Brain tumours disproportionately affect children and are the largest cause of paediatric cancer-related death. Novel therapies that engage the immune system, such as oncolytic viruses (OVs), hold great promise and are desperately needed. The Zika virus (ZIKV) infects and destroys aggressive cells from multiple paediatric central nervous system (CNS) tumours. Despite this, the molecular...

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Literature Corpus work: 29449059-6ff3-59f9-bf96-82abfe7a73f1
DOI: 10.21203/rs.3.rs-5788437/v1

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