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Multi-omics analysis reveals key immunogenic signatures induced by oncolytic Zika virus infection of paediatric brain tumour cells

2024-11-29

Abstract excerpt

Brain tumours disproportionately affect children and are the largest cause of paediatric cancer-related death. Despite decades of research, paediatric standard-of-care therapy still predominantly relies on surgery, radiotherapy, and systemic use of cytotoxic chemotherapeutic agents, all of which can result in debilitating acute and late effects. Novel therapies that engage the immune system, such as oncolytic viru...

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Literature Corpus work
e7cd80a8-d02d-5913-9e34-e74411795a93
DOI
10.1101/2024.11.28.625843
Open publication

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Multi-omics analysis reveals key immunogenic signatures induced by oncolytic Zika virus infection of paediatric brain tumour cellsDOI 10.1101/2024.11.28.625843
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