Article

Integrated re-analysis of transcriptomic and proteomic datasets reveals potential mechanisms for Zika viral-based oncolytic therapy in neuroblastoma

2024-05-21

Abstract excerpt

<h4>Background: </h4> Paediatric neuroblastoma and brain tumours account for a third of all childhood cancer-related mortality. High-risk neuroblastoma is highly aggressive and survival is poor despite intensive multi-modal therapies with significant toxicity. Novel therapies are desperately needed. The Zika virus (ZIKV) can access the nervous system and there is growing interest in employing ZIKV as a potential t...

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Literature Corpus work: 5cbec80f-568c-55f3-99e1-6b9895eea73f
DOI: 10.12688/f1000research.132627.3

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