Article

Integrative transcriptomic and proteomic meta-analysis of Zika viral infection reveals potential mechanisms for oncolytic therapy in neuroblastoma

2022-11-15

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Paediatric neuroblastoma and brain tumours account for a third of all childhood cancer-related mortality. High-risk neuroblastoma is highly aggressive and survival is poor despite intensive multi-modal therapies with significant toxicity. Novel therapies are desperately needed. The Zika virus (ZIKV) is neurotropic and there is growing interest in employing ZIKV as a potentia...

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Literature Corpus work: 5da5586c-cffc-5f9e-915e-6697e2d40672
DOI: 10.1101/2022.11.14.516401

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