Article

Dormant <i>Mycobacterium tuberculosis</i> reactivates <i>ex vivo</i> in blood from HIV infected individuals

2023-11-18

Abstract excerpt

Reports of tuberculosis in Human Immunodeficiency Virus infected patients despite high CD4 + T-cell counts suggest different mechanisms of reactivation. In vitro developed dormant Mycobacterium tuberculosis H37Rv were cultured in HIV blood and normal blood. Colony forming units analysis was performed and expression of mycobacterial Resuscitation Promomoting Factor genes was analyzed by qRT-PCR. The in vitro de...

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Literature Corpus work: 293cc370-f2e8-5c62-96aa-4ad30d67deef
DOI: 10.1101/2023.11.18.566455

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