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An observational study identifying highly tuberculosis-exposed, HIV-1-positive but persistently TB, tuberculin and IGRA negative persons with <i>M. tuberculosis</i> specific antibodies in Cape Town, South Africa

2020-07-08

Abstract excerpt

<h4>Background</h4> Mycobacterium tuberculosis (Mtb) infection is inferred from positive results of T-cell immune conversion assays measuring Mtb-specific interferon gamma production or tuberculin skin test (TST) reactivity. Certain exposed individuals do not display T-cell immune conversion in these assays and do not develop TB. Here we report a hitherto unknown form of this phenotype: HIV-1-positive persistently...

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Literature Corpus work
e07653d3-6cd9-51d2-831d-2402c9b985fc
DOI
10.1101/2020.07.07.20147967
Open publication

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An observational study identifying highly tuberculosis-exposed, HIV-1-positive but persistently TB, tuberculin and IGRA negative persons with <i>M. tuberculosis</i> specific antibodies in Cape Town, South AfricaDOI 10.1101/2020.07.07.20147967
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