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Article

LAG3 marks activated but hyporesponsive NK cells

2024-12-21

Abstract excerpt

Natural Killer (NK) cells are critical for immunosurveillance yet become dysfunctional in contexts such as chronic stimulation by viral infections or cancer. This phenomenon is similar to T cell exhaustion but less well characterized, which limits therapeutic interventions. As shown for T cells, NK cells often display an increased expression of immune checkpoint proteins (ICP) following chronic stimulation, and IC...

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Literature Corpus work
28baddcf-05a0-5ea2-8cb5-a7672130893c
DOI
10.1101/2024.12.18.629184
Open publication

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LAG3 marks activated but hyporesponsive NK cellsDOI 10.1101/2024.12.18.629184
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