Article

Pre-frontal cortical activity during gait is altered in pre-manifest and early spinocerebellar ataxia

2024-11-15

Abstract excerpt

<h4>Background</h4> Spinocerebellar ataxia (SCA) is a degenerative cerebellar disease, causing progressive impairment of gait and balance in adults. To identify the ideal subjects for disease-modifying therapies it is critical to identify biomarkers for the earliest stages of SCA. <h4>Objective</h4> We investigated whether prefrontal cortex activity is increased during walking in in early SCA or in pre-manifest SC...

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Literature Corpus work: 286e8d14-fcda-58fb-8ce0-968c7da8c4a9
DOI: 10.1101/2024.11.14.24317186

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