Article
Cortical network dysfunction revealed by magnetoencephalography in carriers of spinocerebellar ataxia 1 or 2 mutation.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology - 1 Jul 2020
Visani Elisa, Mariotti Caterina, Nanetti Lorenzo, Mongelli Alessia, Castaldo Anna, Panzica Ferruccio, Rossi Sebastiano Davide, Nigri Anna, Grisoli Marina, Franceschetti Silvana, Canafoglia Laura
Abstract excerpt
OBJECTIVE: In patients with spinocerebellar ataxia type 1 or 2 (SCA1 or SCA2) and in their asymptomatic gene-positive relatives (AsyRs) we investigated the event-related desynchronization and synchronisation (ERD/ERS) on magnetoencephalographic signals to assess the changes occurring before manifest ataxia, by comparing the results obtained in AsyRs and in their gene-negative healthy relatives (HRs). METHODS:...
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