Article

Digital gait biomarkers, but not clinical ataxia scores, allow to capture 1-year longitudinal change in Spinocerebellar ataxia type 3 (SCA3)

2022-03-12

Abstract excerpt

Measures of step variability and body sway during gait have shown to correlate with clinical ataxia severity in several cross-sectional studies. However, to serve as a valid progression biomarker, these gait measures have to prove their sensitivity to robustly capture longitudinal change, ideally within short time-frames (e.g. one year). We present the first multi-center longitudinal gait analysis study in spinoce...

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Literature Corpus work: 6cde2f7b-5bf0-5288-b75d-a209fa7dadb1
DOI: 10.1101/2022.03.10.22272119

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